Red Sox vs. Padres Predictions & Picks: Odds, Moneyline, Spread - May 21

Sunday's game at PETCO Park has the Boston Red Sox (26-20) squaring off against the San Diego Padres (20-26) at 4:10 PM ET (on May 21). Our computer prediction projects a close 5-3 victory for the Red Sox, so it should be a tight matchup.

The probable pitchers are Michael Wacha (4-1) for the Padres and Corey Kluber (2-5) for the Red Sox.

Red Sox vs. Padres Game Info & Odds

• When: Sunday, May 21, 2023 at 4:10 PM ET
• Where: PETCO Park in San Diego, California
• How to Watch on TV: BSSD
• Live Stream: Watch this game on Fubo!

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Red Sox vs. Padres Score Prediction

Our pick for this game is Red Sox 5, Padres 4.

Total Prediction for Red Sox vs. Padres

• Total Prediction: Under 9 runs

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Read More About This Game

Red Sox Performance Insights

• The Red Sox have played as the underdog in seven of their past 10 games and have gone 4-3 in those contests.
• In its previous 10 matchups with a total posted by sportsbooks, Boston and its foes are 5-5-0 when it comes to hitting the over.
• The past 10 Red Sox matchups have not had a runline set by oddsmakers.
• The Red Sox have been victorious in 15, or 55.6%, of the 27 contests they have been chosen as underdogs in this season.
• Boston has a mark of 9-3 in contests where bookmakers favor it by +125 or worse on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Red Sox have a 44.4% chance of pulling out a win.
• The offense for Boston is No. 3 in MLB, scoring 5.6 runs per game (258 total runs).
• The Red Sox have the 26th-ranked ERA (4.84) in the majors this season.

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